| Primary Identifier | MGI:7380394 | Allele Type | Transgenic |
| Attribute String | Reporter | Gene | Tg(Nppa*-lacZ)r-0.25Vmc |
| Strain of Origin | FVB | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The â638/-138 bp rat Nppa regulatory region sequence, containing silencer and enhancer sequences, is placed upstream of the â230/+126 bp Tnni3 promoter sequence (and the chimeric silencer-promoter is flanked by chicken beta-globin locus insulator sequence), followed by a beta-globin/IgG chimeric intron, nls sequence, the lacZ beta-galactosidase gene and bovine GH poly(A) signal sequence. The Nppa regulatory sequence drives expression in the embryonic atrial and ventricular chamber myocardium but represses expression in the atrioventricular canal. |
