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Allele : Zfp28<em1(IMPC)J> zinc finger protein 28; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7356590 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Zfp28
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CACGATCACAGGTCACCAGA and GTAAGACTGACAGGGAAAGG, which resulted in a 602 bp deletion beginning at Chromosome 7 position 6,389,393 bp and ending after 6,389,994 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000992229 and ENSMUSE00000464573 (exons 3 and 4) and 379 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 100 and early truncation 1 amino acid later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele