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Allele : Clcn3<tm3.1Tjj> chloride channel, voltage-sensitive 3; targeted mutation 3.1, Thomas J Jentsch

Primary Identifier  MGI:7339242 Allele Type  Targeted
Attribute String  Reporter Gene  Clcn3
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A puromycin resistance cassette flanked by loxP sites was introduced between exon 1 and 2. Venus cDNA was inserted onto the start ATG of the open reading frame which codes for the transcript variant a. Additionally, a silent point mutation was introduced to obtain an NcoI restriction site. The Venus and Clcn3 sequences are separated by a 12 bp linker. The puromycin cassette was removed via cre-mediated recombination.
  • mutations:
  • Insertion
  • synonyms:
  • Clcn3<ven>,
  • Clcn3<ven>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele