|  Help  |  About  |  Contact Us

Allele : Tg(Rr280-GH1)10Mrub transgene insertion 10, Marcelo Rubinstein
Primary Identifier  MGI:7341858 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rr280-GH1)10Mrub
Strain of Origin  either: (C57BL/6 x CBA)F2 or (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains the following elements: a neuron-specific enhancers-containing region 9-13 kb upstream of the Pomc gene transcription start site with enhancer Rr279 (nPE1) deleted (585 bp) but Rr280 (nPE2) still present, the Herpes simplex virus TK gene minimal promoter and the human growth hormone gene. The transgene is expressed in hypothalamic arcuate neurons but not in pituitary melanotrophs and corticotrophs during embryonic development.
  • mutations:
  • Insertion
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom