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Allele : Tg(Pomc-EGFP)1Mrub transgene insertion 1, Marcelo Rubinstein

Primary Identifier  MGI:7341866 Allele Type  Transgenic
Attribute String  Reporter Gene  Tg(Pomc-EGFP)1Mrub
Strain of Origin  either: (C57BL/6 x CBA)F2 or (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains the following: the Pomc gene, including sequence 8 kb downstream of the transcription start site and 13 kb upstream, containing neuron- (Rr279 (nPE1), Rr280 (nPE2)) and pituitary-specific (Rr281) enhancers and the promoter, with the EGFP reporter gene and SV40 poly(A) signal sequences inserted upstream of the translation start site. The transgene is expressed in pituitary melanotrophs and corticotrophs and in hypothalamic arcuate neurons during embryonic development.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele