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Allele : Tg(Rr596*-GH1)5Mrub transgene insertion 5, Marcelo Rubinstein
Primary Identifier  MGI:7341867 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Rr596*-GH1)5Mrub
Strain of Origin  either: (C57BL/6 x CBA)F2 or (C57BL/6 x DBA/2)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene contains the following elements: sequence 9-13 kb upstream of the Pomc gene transcription start site (containing neuron-specific enhancers Rr279 (nPE1) and Rr280 (nPE2)), the Herpes simplex virus TK gene minimal promoter and the human growth hormone gene gene. The transgene is expressed in hypothalamic arcuate neurons but not in pituitary melanotrophs and corticotrophs during embryonic development.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(GH1)5Mrub,
  • Tg(GH1)5Mrub
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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2 Publication categories

Trail: Allele




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