| Primary Identifier | MGI:7385074 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Letmd1 |
| Strain of Origin | Not Specified | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology in combination with mouse oviduct electroporation (i-GONAD; improved-Genome editing via Oviducal Nucleic Acids Delivery) deleted exons 3 to 7, causing a frameshift and inducing a stop codon, resulting in a truncated protein of 104 aa excluding the transmembrane domain a majority of the LETM1 domain. Western blot analysis confirmed the absence of protein. |
