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Allele : Calr<tm2.1Ics> calreticulin; targeted mutation 2.1, Mouse Clinical Institute
Primary Identifier  MGI:7384568 Allele Type  Targeted
Attribute String  Conditional ready Gene  Calr
Transmission  Germline Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting inserted a loxP site, a fusion of exon 8 and 9, a stop site and triple polyadenylation sequence, an FRT-flanked neomycin resistance cassette, a loxP site, wild-type exon 8, and a mutated exon 9 with the human mutated C-terminal tail containing a 52 bp deletion. Flp-mediated recombination removed the selection cassette.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CALR del52,
  • CALR del52
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories

Trail: Allele




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