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Regulatory Region : Rr344 regulatory region 344

Primary Identifier	MGI:7428575	Organism	mouse, laboratory
Chromosome	2	Mgi Type	enhancer

description

PHENOTYPE: Mice homozygous for a null allele pancreas hypoplasia, decreased body weight, decreased alpha and beta cell mass in the pancreas, and impaired pancreatic bud formation. [provided by MGI curators]

synonyms:
regulatory region 344,
Rr344,
NA Ptf1a<enh>

earliestPublication:
Miguel-Escalada I, et al. (2022) Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster. Dev Cell 57(16):1922-1936.e9

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Genome

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0 Genomic Clusters

0 Involved In Mutations

0 Transgenic Expressors

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Function

Mouse features --> Functions (GO terms)

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

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