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Allele : Rag1<em1Mvw> recombination activating 1; endonuclease-mediated mutation 1, Michael Wiles

Primary Identifier  MGI:7428597 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Rag1
Inheritance Mode  Not Specified Strain of Origin  129S1/SvImJ
Is Recombinase  false Is Wild Type  false
molecularNote  The CRISPR/Cas9 base editor BE4Max was used to convert the glutamine codon at position 192 to a stop codon (Q192X, CAG to TAG), resulting in an early termination allele predicted to be a null.
  • mutations:
  • Single point mutation
  • synonyms:
  • 129R,
  • 129R
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele