| Primary Identifier | MGI:7428383 | Allele Type | Targeted |
| Attribute String | Modified isoform(s), Reporter | Gene | Shank3 |
| Transmission | Germline | Strain of Origin | C57BL/6N |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The targeted vector with an auto-excision floxed Neomycin resistance cassette and a 1.5 kb fragment corresponding to the fusion of the Venus tag sequence at the beginning of exon1 of the Shank3 gene, just after the ATG start codon was inserted. The floxed selection cassette was excised in the germline chimera mice. The reporter is to tag exclusively the endogenous Shank3 variants that are produced by the first promoter: variants of the Shank3a isoform only. |
