Primary Identifier | MGI:7398501 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Emu-RET)385Ina |
Strain of Origin | (C57BL/6 x BALB/c)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A human transforming RET cDNA was isolated from a cDNA library of a THP-1 human monocytic leukemia cell line in which the sequences encoding the last 51 carboxy-terminal amino acids of the ret proto-oncogene were replaced with sequences encoding 9 unrelated amino acids. This cDNA was expressed under the control of the Emu enhancer (Rr150) from the immunoglobulin heavy chain (Igh) gene. |