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Allele : Tg(Dct-cre/ERT2)40ALru transgene insertion 40A, Lionel Larue
Primary Identifier  MGI:7425240 Allele Type  Transgenic
Attribute String  Inducible, Recombinase Gene  Tg(Dct-cre/ERT2)40ALru
Strain of Origin  C57BL/6J Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  A 6.7 kb transgenic vector was generated including the mouse dopachrome tautomerase (Dct) promoter driving expression of a cre/ERT2 fusion gene (a Cre recombinase fused to a human estrogen receptor ligand binding domain) followed by an SV40 polyadenylation sequence. The founder line 40A, with approximately 60 copies of the transgene inserted into the H4 region (AC121292.9) of chromosome 1 in an intergenic region between the H3.3 histone A (H3f3a) and the SDE2 telomere maintenance homolog (S. pombe) (Sde2) genes, was established.
  • mutations:
  • Insertion
  • synonyms:
  • Dct::CreER<T2>,
  • Dct::CreER<T2>
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