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Allele : Neb<tm4.1Hgra> nebulin; targeted mutation 4.1, Henk Granzier

Primary Identifier  MGI:7407199 Allele Type  Targeted
Attribute String  Not Specified Gene  Neb
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed that deleted exons 53-64 (15,326bp deletion: chr2:52,250,795-52,266,120) encoding 3 super repeats. The Osdd vector (providing TK for negative selection) was used and homology arms (4kb left and 3.5kb right) allowed the replacement of the deleted sequence with a FRT-flanked neoR positive-selection cassette. Flp-mediated recombination remove the neoR cassette.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Neb<Del(S9-11)>,
  • Neb<Del(S9-11)>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

3 Publication categories

Trail: Allele