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Allele : Adat2<em1(IMPC)J> adenosine deaminase, tRNA-specific 2; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7408173 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Adat2
Inheritance Mode  Not Specified Is Recombinase  false
Is Wild Type  false Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATATCATAAACTCACCAACA and ATGCAGCAAGTACAAGAGCC, which resulted in a 476 bp deletion beginning at Chromosome 10 position 13,435,665 bp and ending after 13,436,140 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000098195 (exon 3) and 325 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 67 and early truncation 20 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele