Primary Identifier | MGI:7435233 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Igh |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Igha promoter Rr361 (~840 bp), (part of) the last intron and exon of human hemoglobin subunit beta (~1100 bp) and a loxP site flanked neomycin resistance gene cassette were inserted downstream of super-enhancer 3'RR (Rr152), between it and Igh super-insulator Rr363. The neo cassette was removed through subsequent cre-mediated recombination. |