Primary Identifier | MGI:7413090 | Allele Type | Endonuclease-mediated |
Attribute String | Modified regulatory region | Gene | Del(11Rr1367-Rr238931)1Cya |
Strain of Origin | C57BL/6 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The Pierre Robin Sequence (PRS) region (chr11:111446352-111723870 (GRCm39)), which is part of the Sox9 topologically associating domain (TAD) that contains enhancers and other regulatory sequences, was targeted with sgRNAs using CRISPR/Cas9 technology, resulting in its deletion. |