| Primary Identifier | MGI:7435735 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Pla1a |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences AGAGGCACTGAACCTCCGAG and TGAGTTGTACATGCAACGAG, which resulted in a 544 bp deletion beginning at Chromosome 16 position 38,415,170 bp and ending after 38,415,713 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000130582 (exon 3) and 366 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 92 and early truncation 61 amino acids later. |
