Primary Identifier | MGI:7442605 | Allele Type | Transgenic |
Attribute String | Reporter | Gene | Tg(Rr387-lacZ)12Jejo |
Strain of Origin | (C57BL/6 x DBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | The transgene insertion contains the following elements: a SacII-SmaI restriction fragment containing sequence downstream of Atoh1 (which includes enhancer Rr387 or E0) where the last 144 bp were deleted and the E-box at he 3' end was mutated from CAGctg to ATTctg, Hbb basal promoter, the beta-galactosidase reporter gene, and SV40 ploy(A) signal sequences. Reporter gene embryonic expression is abolished in the dorsal neural tube but still present, weakly, in hindbrain. |