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Allele : Tg(Per1-Kcnma1*R207Q)#Alme transgene insertion, Andrea L Meredith

Primary Identifier  MGI:7464147 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Per1-Kcnma1*R207Q)#Alme
Is Recombinase  false Is Wild Type  false
molecularNote  The transgene contains the following elements: a 6,756 bp DNA fragment containing the putative Per1 promoter sequence and the 5'-untranslated region, which encompasses exon 1 and part of exon 2, a modified Kcnma1 cDNA where arginine codon 207 was changed to glutamine (p.R207Q), and hemoglobin beta poly(A) signal sequences. This is a fast-activating gain-of-function mutation.
  • mutations:
  • Insertion
  • synonyms:
  • Tg-BK<R207Q>,
  • Tg-BK<R207Q>
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele