| Primary Identifier | MGI:7464254 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Dsp |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Arginine codon 463 (CGG) in exon 11 was changed to glycine (GGG) (p.R463G) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the human p.R451G mutation associated with arrhythmogenic cardiomyopathy (ACM). |
