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Allele : Elp4<em1(IMPC)Tcp> elongator acetyltransferase complex subunit 4; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7464998 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Elp4
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of CACACCCACCGACTCGTTCA targeting the 5' side and CTGCATTCAGTAGCTTAGTG targeting the 3' side of a critical region (ENSMUSE00000224292). This resulted in a 1849-bp deletion of Chr2 from 105661891 to 105663739 (GRCm39) introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele