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Allele : Kcng1<em1(IMPC)Tcp> potassium voltage-gated channel, subfamily G, member 1; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7465000 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Kcng1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AGGTGGCGCTGACTTAACAT targeting the 5' side and TGGTTGCATGAAGCCGCAGC targeting the 3' side flanking the CDS (ENSMUSE00000679346 & ENSMUSE00000639006). This resulted in a 7,713-bp deletion of Chr2 from 168,104,267 to 168,111,979 (GRCm39) introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele