| Primary Identifier | MGI:7464047 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence, Hypomorph | Gene | Gins3 |
| Strain of Origin | C57BL/6N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Exon 1 was targeted with an sgRNA and ssODN template using CRISPR/Cas9 technology to change aspartic acid codon 24 (GAC) to asparagine (AAC) (p.D24N). The mutation mimics the human NM_022770.2: c.70G>A, p.(Asp24Asn) mutation found in some Meier-Gorlin syndrome patients. |
