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Allele : Ascl3<tm2.1(icre/ESR1*)Ovi> achaete-scute family bHLH transcription factor 3; targeted mutation 2.1, Catherine E Ovitt
Primary Identifier  MGI:7447443 Allele Type  Targeted
Attribute String  Inducible, Recombinase, Reporter Gene  Ascl3
Transmission  Germline Strain of Origin  (129S6/SvEvTac x C57BL/6NCrl)F1
Induced With  tamoxifen Is Recombinase  true
Is Wild Type  false
molecularNote  The targeting vector consists of a P2A sequence followed by an icre (codon-optimized cre) /mutated human ESR1 fusion protein and an FRT-flanked PGK-neomycin selection cassette. The targeting construct was inserted immediately upstream of the termination codon of the achaete-scute family bHLH transcription factor 3 (Ascl3) gene. The neo-selection cassette was removed by Flp recombinase.
  • mutations:
  • Insertion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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3 Publication categories

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