Primary Identifier | MGI:7450797 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Fos |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A cDNA sequence encoding a mutant destabilizing form (DD) of bacterial dihydrofolate reductase (ecDHFR; folA) attached to cre recombinase cDNA was inserted into the Fos gene locus at the translation start site. Funder mice were crossed to a germline-active flpe expressing transgenic line to remove the PGK-neo cassette. |