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Allele : Mki67<em1(cre/ERT2)Bzsh> antigen identified by monoclonal antibody Ki 67; endonuclease-mediated mutation 1, Bin Zhou
Primary Identifier  MGI:7451128 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready, Inducible, Recombinase Gene  Mki67
Strain of Origin  Not Specified Induced With  tamoxifen
Is Recombinase  true Is Wild Type  false
molecularNote  Using CRISPR/Cas9 technolgy, the CrexER (Cre-rox-ER-rox) was generated by the insertion of two rox sequences flanking ERT2, a cDNA encoding CrexER recombinase replaced the translational stop codon of the Mki67 gene, following endogenous Mki67 by the self-cleaving peptide 2A sequence.
  • mutations:
  • Insertion
  • synonyms:
  • Ki67-CrexER,
  • Ki67-CrexER
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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1 Driven By

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Trail: Allele




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