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Allele : Twist1<em2Wdf> twist basic helix-loop-helix transcription factor 1; endonuclease-mediated mutation 2, Walid D Fakhouri
Primary Identifier  MGI:7469500 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Twist1
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 42 (AGT) was changed to alanine (GCT) (p.S42A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation prevents phosphorylation of the highly conserved residue in the CBP region.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Twist1<S42A>,
  • Twist1<S42A>
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Trail: Allele

Genome

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0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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