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Allele : Twist1<em3Wdf> twist basic helix-loop-helix transcription factor 1; endonuclease-mediated mutation 3, Walid D Fakhouri
Primary Identifier  MGI:7469501 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Twist1
Is Recombinase  false Is Wild Type  false
molecularNote  Serine codon 68 (AGC) was changed to alanine (GCT) (p.S68A) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation prevents phosphorylation of the highly conserved residue, which is normally phosphorylated by MAPK.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Twist1<S68A>,
  • Twist1<S68A>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele




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