| Primary Identifier | MGI:7461949 | Allele Type | Endonuclease-mediated |
| Attribute String | Reporter | Gene | Gt(ROSA)26Sor |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A guide RNA [5'- GCAGATCACGAGGGAAGAGG-3'] is selected to introduce a full-length luciferase gene, containing the R387X (c.A1159T) nonsense mutation and T381T silent mutation, into the Gt(ROSA)26Sor locus. The silent T381T mutation creates a new PAM site required for the binding of the base editor. |
