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Allele : Cyp19a1<tm1.1Vdlm> cytochrome P450, family 19, subfamily a, polypeptide 1; targeted mutation 1.1, Ratna K Vadlamudi
Primary Identifier  MGI:7486738 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Cyp19a1
Transmission  Germline Strain of Origin  129
Is Recombinase  false Is Wild Type  false
molecularNote  Exons 10 and 11 were flanked by loxP sites. An FRT-flanked neomycin selection cassette was inserted after the first loxP site, upstream of exon 10, and was removed via flp-mediated recombination. Exons 10-11 encode for the second substrate-binding site, the iron-binding site, part of the p450 domain, and the polyA signal.
  • mutations:
  • Insertion
  • synonyms:
  • Aro Flox,
  • CYP19a1 loxP,
  • Aro Flox,
  • Cyp19a1<tm1.1Geno>,
  • Cyp19a1<tm1.1Geno>,
  • CYP19a1 loxP
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

5 Publication categories

Trail: Allele




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