| Primary Identifier | MGI:7471421 | Allele Type | Targeted |
| Attribute String | Conditional ready, Humanized sequence, Inserted expressed sequence | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site was inserted upstream of exon 2, exons 4-9 were replaced with the orthologous human exons, the human exon 7 introduced contains a mutation resulting in an R248Q substitution, and an FRT and loxP site flanked neomycin resistance gene cassette was inserted into intron 10. Flp-mediated recombination removed the neo cassette leaving exons 2-10 floxed. |
