Primary Identifier | MGI:7482326 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Taar6 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A sequence encoding Cre was introduced into the 3â untranslated sequence in the Taar6 gene immediately following the stop codon with an IRES sequence preceding the Cre sequence to allow bicistronic expression of TAAR6 and Cre. The targeting construct included a cassette of the neomycin gene flanked by FRT sites. The neomycin gene was removed by crossing the mice to a germline Flp recombinase line. |