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Allele : Ugt2b38<em1(IMPC)Tcp> UDP glucuronosyltransferase 2 family, polypeptide B38; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7482623 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Ugt2b38
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of AATTCTGGTCAGGGTACTCA targeting the 5' side and CTATAGGCTGGCCCATTGTC targeting the 3' side of a critical region (ENSMUSE0000105763 and ENSMUSE00001085011). This resulted in a 3841bp deletion of Chr5 from 87566792 to 87570632 with the insertion of aaaaaagaaagaaaaagaa (GRCm39), introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele