| Primary Identifier | MGI:7488143 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Nf1 |
| Strain of Origin | C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Arginine codon 1811 (CGC) was changed to cysteine (TGC) (p.R1811C) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. The mutation is the equivalent of the human c.5425C>T p.Arg1809Cys mutation associated with neurofibromatosis 1 (NF1). |
