| Primary Identifier | MGI:7488573 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Pah |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Arginine codon 408 (CGG) was changed to tryptophan (TGG) (p.R408W) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the same human mutation associated with phenylketonuria (PKU). |