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Allele : Pah<em1Liuq> phenylalanine hydroxylase; endonuclease-mediated mutation 1, Liuqing Yang

Primary Identifier  MGI:7488573 Allele Type  Endonuclease-mediated
Attribute String  Humanized sequence Gene  Pah
Is Recombinase  false Is Wild Type  false
molecularNote  Arginine codon 408 (CGG) was changed to tryptophan (TGG) (p.R408W) using an sgRNA and an ssODN template with CRISPR/Cas9 technology. This mutation is the equivalent of the same human mutation associated with phenylketonuria (PKU).
  • mutations:
  • Single point mutation
  • synonyms:
  • Pah<R408W>,
  • Pah<R408W>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele