| Primary Identifier | MGI:7523884 | Allele Type | Endonuclease-mediated |
| Attribute String | Null/knockout | Gene | Lrrc46 |
| Inheritance Mode | Not Specified | Strain of Origin | C57BL/6NJ |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | IMPC |
| molecularNote | This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GACAAACTAGGTTCACAGCA and CCTTCTGGAAAGCTGCTAGG, which resulted in a 430 bp deletion beginning at Chromosome 11 position 97,038,696 bp and ending after 97,039,125 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000111048 (exon 3) and 321 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 42 and early truncation 46 amino acids later. |
