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Allele : Rr50<em1Axvi> regulatory region 50; endonuclease-mediated mutation 1, Axel Visel

Primary Identifier  MGI:7489592 Allele Type  Endonuclease-mediated
Attribute String  Modified regulatory region Gene  Rr50
Strain of Origin  FVB Is Recombinase  false
Is Wild Type  false
molecularNote  The topologically associating domain (TAD) boundary region or insulator between Snx13 and Ahr, separating the Twist1 TAD from the Ahr TAD, was targeted with sgRNAs (targeting GGGCACTGGGTTTCTTCTATCGG, TATTGCCTCAATGGAATAGGTGG, AGTAAGCAATGGTTTTGCATTGG and GTCTCTGACACTTGTTTGCTTGG) using CRISPR/Cas9 technology, resulting in a 13112 bp deletion (chr12:35231340-35244451(GRCm39)).
  • mutations:
  • Intergenic deletion
  • synonyms:
  • B6,
  • B6
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele