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Allele : Tomt<em1(IMPC)Tcp> transmembrane O-methyltransferase; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7490176 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Tomt
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of TCCAATGGTCAAGCGTGGTG and AGCCACATGGGCCCTGTTAA within exon ENSMUSE00000671717. This resulted in a 15bp deletion of Chr7 from 101551254 to 101551268 (GRCm39) and a 1bp deletion of Chr 7 at 101551228, introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele