|  Help  |  About  |  Contact Us

Allele : Del(11Hnf1b-Znhit3)11Moro deletion, Chr 11, Eric Morrow
Primary Identifier  MGI:7490277 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Del(11Hnf1b-Znhit3)11Moro
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 genome editing is used to delete the 11qC region of the mouse genome between chr11:83791635-84938224 Mb [GRCm38.p6 (mm10), NCBI Reference Sequence, NC_000077.6]. The mouse deletion matches the consensus human deletion between chr17:31.8-33.2 Mb (GRCh38.p13, NCBI Reference Sequence, NC_000017.11). The 17q12 deletion removed all genes downstream of Gm11434 and upstream of Gm33028 including Aatf, Acaca, Gm11437, Ddx52, Dhrs11, Dusp14, Ggnbp2, Lhx1, Hnf1b, Mrm1, Myo19, Pigw, Synrg and Znhit3. sgRNAs were targeted to upstream of Hnf1b and downstream of Znhit3.
  • mutations:
  • Intergenic deletion
  • synonyms:
  • 17q12Del,
  • 17q12Del
Paste the following link
Quick Links:
SummaryGenomePhenotypeOther
 
Quick Links:
SummaryGenomePhenotypeOther
 
Lists
This Allele isn't in any lists. Upload a list.

1 Feature

Trail: Allele

Genome

0 Expresses

14 Mutation Involves

Trail: Allele

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom