Primary Identifier | MGI:7490340 | Allele Type | Targeted |
Attribute String | Inserted expressed sequence | Gene | Gt(ROSA)26Sor |
Transmission | Germline | Strain of Origin | 129S4/SvJae |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A CAG-Loxp-PGK-Neo-poly(A)-Loxp-Runx1 cassette was inserted into the Rosa26 locus. The cDNA containing a complete open reading frame of Runx1 was inserted after the second Loxp site. Constitutive Runx1 expression is observed upon removal of the STOP cassette by Cre-mediated recombination. |