|  Help  |  About  |  Contact Us

Allele : Trim42<em1(IMPC)J> tripartite motif-containing 42; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7491697 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Trim42
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences GGTGGAGAAATCTAGACACT and GGTGATAAACGGTTCCTGCA, which resulted in a 948 bp deletion beginning at Chromosome 9 position 97,365,460 bp and ending after 97,366,407 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000219798 (exon 2) and 250 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 114 and early truncation 2 amino acids later.
  • mutations:
  • Intragenic deletion
Quick Links:
 
Quick Links:
 

1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele