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Allele : Nudcd1<em1(IMPC)J> NudC domain containing 1; endonuclease-mediated mutation 1, Jackson

Primary Identifier  MGI:7491744 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Nudcd1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NJ
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTATATACAGAGATAATAAA and AGATTGCTGTCAATATTTTG, which resulted in a 668 bp deletion beginning at Chromosome 15 position 44,399,798 bp and ending after 44,400,465 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000252601 (exon 6) and 460 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 272 and early truncation 5 amino acids later.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

2 Publication categories

Trail: Allele