| Primary Identifier | MGI:7491944 | Allele Type | Endonuclease-mediated |
| Attribute String | Humanized sequence | Gene | Ano5 |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | CRISPR/Cas9 technology generated a G to A change at position 1080 (corresponds to c.1079G>A on GRC39) resulting in a cysteine to tyrosine substitution at amino acid 360 (p.C360Y) in exon 11. This mutation cosegregates with gnathodiaphyseal dysplasia in a Han-Chinese family. |
