Primary Identifier | MGI:7507547 | Allele Type | Transgenic |
Attribute String | Inducible, Recombinase, Reporter | Gene | Tg(Prrx1-mTFP1,-cre/ERT2)1Etnka |
Strain of Origin | C57BL/6J | Induced With | tamoxifen |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A transgene consists of the 2.4 kb mouse Prrx1 enhancer followed by the b-globin intron and nuclear-localized teal fluorescent protein-1 (mTFP1-nls), a T2A self-cleaving peptide, and CreERT2. Six founder animals were generated and a single line with the ability to induce the recombination of LoxP reporter lines only after administration of tamoxifen was established and used for the studies. |