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Allele : Saa3<em2Litt> serum amyloid A 3; endonuclease-mediated mutation 2, Dan R Littman
Primary Identifier  MGI:7717772 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Saa3
Strain of Origin  (C57BL/6NTac x 129S6/SvEvTac)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to introduce premature stop codons (TAG TAA), a frame shift mutation (A), and a HindIII site (AAGCTT) in to exon 2. Recombination was done using mice carrying Del(7Saa1-Saa2)1Itl creating triple knockout mice.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • SAA<TKO>,
  • SAA<TKO>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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