Primary Identifier | MGI:7511856 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CMV-cat,-Rhoa)4-28Koba |
Strain of Origin | Not Specified | Is Recombinase | false |
Is Wild Type | false |
molecularNote | A 0.9 kb DNA fragment containing the cytomegalovirus early gene promoter was fused to the rabbit beta-globin second intron and chloramphenicol acetyltransferase (CAT) gene cassette connected to a polyadenylation signal, both ends of which were flanked by loxP sites. This was then followed by a 0.6 kb DNA fragment encoding a dominant-negative mutant for RhoA and a second polyadenylation signal. |