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Allele : Pole<em1Tcp> polymerase (DNA directed), epsilon; endonuclease-mediated mutation 1, The Centre for Phenogenomics
Primary Identifier  MGI:7520417 Allele Type  Endonuclease-mediated
Attribute String  Not Specified Gene  Pole
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  This allele was generated at The Centre for Phenogenomics by injecting Cas9 mRNA with a guide RNA with the spacer sequence AGCATCTGACACTGAGTAAGand a single-strand oligonucleotide encoding the changes c.1376_1377CA>TC (p.S459F) and a silent mutation c.1368C>T (p.A456) to disrupt the protospacer adjacent motif (PAM) sequence.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Pole<S459F>,
  • Pole<S459F>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

2 Publication categories

Trail: Allele




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