| Primary Identifier | MGI:7543977 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Itpr1 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A GAC to GCC change resulting in an aspartate to alanine substitution at amino acid 2594 (p.D2594A) was introduced in the channelâs gating domain. The inserted FRT-flanked neomycin selection cassette was removed via flp-mediated recombination. This is a loss of function mutation. |
