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Allele : Gng12<em1(IMPC)Tcp> guanine nucleotide binding protein (G protein), gamma 12; endonuclease-mediated mutation 1, The Centre for Phenogenomics

Primary Identifier  MGI:7512907 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Gng12
Inheritance Mode  Not Specified Strain of Origin  C57BL/6NCrl
Is Recombinase  false Is Wild Type  false
Project Collection  IMPC
molecularNote  This allele was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with single guide RNAs having spacer sequences of GTTGGTGCTTGCCGTCTTGC (within ENSMUSE00000256838) and CGGAGCGACCCCCTGCTGAT(within exon ENSMUSE00001368854). This resulted in a 1769bp deletion of Chr6 from 66992743 to 66994511 with insertion of A and a T>C at 66992738 (GRCm39), introducing a frameshift and premature stop codon.
  • mutations:
  • Intragenic deletion
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele